Call 1-800-MI-SAULT For more information and up-to-date maps, contact the Sault Ste. Marie Convention & Visitors Bureau. Sault Ste. Marie is located at the northern end of I-75. Exit 392 merges onto the I-75 Business Spur at the city limits, and Exit 394 enters onto Easterday Avenue near downtown Sault Ste. Marie.